4 mg/kg/day or 100 mg/day; may be administered once daily or divided twice daily (AAP [Flynn 2017]; NHBPEP 2004; NHLBI 2011); Note:Doses >1
5 mg daily should be added and/or the dose of losartan
2
Strengths: 25 mg, 50 mg, 100 mg; Dosage for high blood pressure (hypertension) Adult dosage (ages 18–64 years) The typical starting dosage is 50 mg
Terminal half-life of losartan and its active metabolite is approximately 2 and 6–9 hours, respectively
The losartan half-life is about 2 hours and the metabolite half-life is 6 to 9 hours
Downsides
1 Hypertension - Adult Hypertension The usual starting dose of losartan potassium tablet is 50 mg once
2
Patients were randomized to receive once daily losartan potassium 50 mg or The terminal half-life of losartan is about 2 hours and of the metabolite is about 6 to 9 hours
After single doses of losartan administered orally, about 4% of the dose is excreted unchanged in the urine and about 6% is excreted in urine as active metabolite
During once daily dosing with 100 mg, neither losartan nor its active Key takeaways: Losartan (Cozaar) is an angiotensin II receptor blocker used to treat high blood pressure
After single doses of losartan administered orally, about 4% of the dose is excreted unchanged in the urine and about 6% is excreted in urine as active metabolite
Patients were randomized to receive once daily Losartan potassium 50 mg or atenolol While the peak plasma concentration of losartan is reached after one hour, the active metabolite peaks at 4 hours
After single doses of losartan administered orally, about 4% of the dose is excreted unchanged in the urine and about 6% is excreted in urine as active metabolite
This can lead to hypotension (low blood pressure)
The starting dose is usually 0
If you have certain health conditions, like liver or kidney problems The terminal half-life of losartan is about 2 hours and of the metabolite is about 6-9 hours
with a terminal half life of about 2 hours and 6-9 hours, respectively
Although the LIFE study favored losartan potassium tablets over COZAAR is available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of losartan potassium and the following inactive ingredients: microcrystalline cellulose, lactose hydrous, pregelatinized starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, and titanium dioxide