Peripartum cardiomyopathy (PPCM) is a pregnancy-associated idiopathic cardiomyopathy presenting during pregnancy or within few months after delivery 1,2 with signs and symptoms of heart failure caused by marked depression of left ventricular (LV) systolic function
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Mechanism of action Bromocriptine, a clinically-approved drug to block prolactin release, was initially tested in a PPCM mouse model where it efficiently prevented the onset of PPCM
Abstract: Bromocriptine is a sympatholytic dopamine D2 receptor agonist with remarkable bioactivities
Each of the medications described in this review have differing mechanisms of action that may contribute to their efficacy in the management of central fever, though much information remains to be elucidated regarding their exact mechanisms
Bromocriptine mesylate is chemically designated as Ergotaman-3′,6′,18-trione, 2-bromo-12′-hydroxy-2′-
2% when compared to baseline and 0
The proposed mechanism of action of bromocriptine to improve glucose tolerance is summarized in Fig
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However, it has a number of undesirable side effects, even causing mental disturbances in long-term use
It also stimulates nigrostriatal pathways in the corpus striatum to enhance
Here, we tested three